Genetic Considerations
Using Inbreeding Coefficients. CA Sharp. Australian Shepherd Health and Genetics Institute.
The Popular Sire. Carol Beuchat, PhD, Scientific Director and Founder of Institute of Canine Biology.
Breadth of Pedigree. Dr. Carmen Battaglia.
Pedigree Analysis. Dr. Carmen Battaglia. Do you know the difference between a traditional, a stick dog color chart pedigree, and a symbols pedigree? Which one(s) displays information needed to make breeding decisions?
Study of MHC Class II Genes of Bearded Collies Reveals Narrow Diversity. From a Finnish study.
Genetic Diversity
Genetic Diversity and SLO. Sell, Elsa, MD. (See p10)
A Case History of Genetic Diversity in Florida Panthers. (See p 17)
Breed Dilemmas and Extinction. Dr. Carmen Battaglia. "Breeders have the power to change and create their breed’s reality. A look at the big picture suggests that it all boils down to whether they will choose to continue on a path of trial and error or whether they are willing to try and make a difference."
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Coefficient of Inbreeding
BeaCon uses Breeder’s Assistant software to calculate COI’s. It is possible to choose the number of ancestor generations and to fine tune the calculation by controlling the treatment of ancestors beyond the number of generations that are visible to the calculation because of multiple occurrences of the same ancestor in different generations of the pedigree. The fine tuning possibilities with Breeder’s Assistant are:
- Strict options mean that the program is to strictly observe the ancestor generation limit imposed on the calculation; these cannot go beyond the last generation even though that information may be available in the database.
- Strict with Minimal Common Ancestor Inbreeding considers only the inbreeding of a common ancestor that is visible within the pedigree at both the sire and dam side occurrences, on a path by path basis.
- Strict with Maximum Common Ancestor Inbreeding uses the maximum inbreeding of the common ancestor as can be deduced by examining its sire and dam side occurrences, again on a path by path basis.
- Relaxed options are faster when computing inbreeding to any significant depth of ancestors.
- Relaxed with Maximal COI includes all possible common ancestors that can be deduced from the pedigree, subject only to the generation limit.
- Relaxed with Maximal Speed computes the inbreeding coefficient as fast as possible by ignoring knowledge of the parents of ancestors that only occur in the last generation.
The pedigrees shown in the Open Health Registry have COI calculated for 10 generations and using the relaxed with maximal speed method. When comparing COI values obtained with other software programs the calculation methodology needs to be identical.
Click here for 5 and 10 generation COIs of the dogs in the public section of BeaCon Open Health Registry, April 2016. It is alphabetical by dog's registered name. Since there are 2705 dogs, the document is long.