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Autoimmune Disease

General Articles about Autoimmunity

Major Histocompatibility Complex (MHC) and Autoimmune Disease in Dogs. Steven Goodman, 2010, AKC CHF. A good introduction to understanding autoimmunity and the role of the MHC.   


The Complexity of Autoimmune Disease. Jo Tucker (See p15)      


Autoimmune Disease.  Linda Aronson. 1999.  What is it? …    Diseases. Causes. This article was presented at the BCCC Specialty, August 1999. It contains a description of the mechanism of what an autoimmune disease.  There is a discussion of cause of A/I disease and a section on vaccination.  


Bearded Collies and Autoimmune Disease.  Linda Aronson.  Presenting signs, tests and treatment. It details both the signs of 10 autoimmune diseases and the tests used to make a diagnosis. This is helpful for understanding tests which your veterinarian may order on your dog to establish a diagnosis.


Stress, Drugs and Immunity.  Linda Aronson,   2005 (See p7)


What's Up Doc?  Beardie Bulletin, August 1996. Linda Aronson.   Common and uncommon presentations (physical findings) of autoimmune diseases in Bearded Collies.

Addison's Disease

Links for submitting DNA sample to UC Davis (Dr. Oberbauer’s lab)

Link for updating health of dogs with DNA samples previously submitted to UC Davis (Dr. Oberbauer’s lab)

Addison's, Diagnosing.  Help Your Vet to Not Overlook It by Carol Lang, Beardie Bulletin, May 1987

Atypical Addison’s in the Dog: A Retrospective Survey of 14 Cases.  Sadek, D and Schaer, M. J Am Anim Hosp Assoc 1996;32:159-63.

Kidney Disease, Or Is It?  Jo Tucker (See p2)

Addison's: Test My Beardie for Addison's - Again?  FAQ's.  By Lynne Corn (See p9)

Addison's Update:  A Personal Perspective.  By: Karen Miller- Stebbings.  Beardie Bulletin, November 1996

Addison's Update.  Linda Aronson, DVM

Yes! We Loved Tegan by Jean M. Kennedy Beardie Bulletin, August 1988

Katie's Story.  Beardie Bulletin, May 1999


Arthritis. Linda Aronson, DVM. Published in theVetSpeak Section of the Shaggy Sentinel, December, 1997. Minuteman Bearded Collie Club.

Autoimmune Hemolytic Anemia.

Autoimmune Hemolytic Anemia.  Jo Tucker  (See p14)

The Role of Oxidative Stress in Immune Mediated Hemolytic Anemia. 2013. AKC CHF.

Evan's Syndrome.   Joanne Johnson

Symmetrical Lupoid Onychodystrophy (SLO)

Photos of SLO Nails in Beardies

    Brook’s Toe Amputation for SLO Diagnosis.  Judy Howard and Elizabeth-Coolidge-Stolz, MD (p12).

    Finnish Study of SLO in Bearded Collies and Major Histocompatibility Research.

 Introduction to Terms used in above article. Read this first to help understand the article. Elizabeth     Coolidge-Stolz, MD

Symmetrical Lupoid Onychodystrophy in Dogs. A Retrospective Analysis of 18 Cases (1989-1993)By: Scott, D.W., DVM, Rousselle, S, DVM, and Miller, W.H., VMD, DiplomateACVD. From the Departments of Clinical Sciences (Scott, Miller) and Pathology(Rousselle), College of Veterinary Medicine, Cornell University, Ithaca, NewYork 14853. JAAHA, May/June 1995, Vol. 31, pp. 192-201.    

A Retrospective Study Regarding the Treatment of Lupoid Onychodystrophy in 30 Dogs and Literature Review. Mueller, RS, Rosychuk, RAW, and Jonas, LD. J Am Animal Hospital Association 2003;39:139-150. (Note: A copy of this article is available upon request to ).   

    SLO and Genetic Diversity, Elsa Sell, MD

    SLO Survey, 2004.      (See p10)

    SLO Survey, 2011.

    SLO SCBCC Seminar 2011.  Jo Tucker

 SLO Support Groups.  There are two Facebook canine SLO support groups


Hypothyroidism, A New Direction, E.  Bodner.  This article first appeared in the AKC Gazette, February, 997 and is reprinted here with the permission of the author and the publisher.  This was the first article published with recommendations regarding thyroid testing for breeding animals.

Hypothyroidism and Aggression. Linda Aronson, DVM and Nick Dodmon, RVMS

OFA Thyroid Ranking for Bearded Collies. Through December 2014, Beardies rank 77/107 with 724 dogs tested.

        Normal - 86.3%

        Autoimmune thyroiditis - 1.4%

        Idiopathic hypothyroidism - 0.7%

        Equivocal - 14.4% (these should be retested at a later time)

Review of function of thyroid gland, signs of hypothyroidism, and diagnosis.  Linda Aronson, DVM

Systemic Lupus Erythematosus (SLE)

SLE, Jo Tucker  (See p20)

Systemic lupus erythematosus.

Genes associated with increased risk of SLE-like disorder in Nova Scotia Duck Tolling Retrievers.

Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex. Wilbe, et. al., Nature Genetics, 2010, 42(3):250-4  

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